In vivo activity of a novel polymeric guanidine in experimental skin infection with methicillin-resistant Staphylococcus aureus.

نویسندگان

  • Christina Kratzer
  • Selma Tobudic
  • Karin Macfelda
  • Wolfgang Graninger
  • Apostolos Georgopoulos
چکیده

The in vivo efficacy of the novel polymeric guanidine AKACID Plus was evaluated in a guinea pig model of experimental skin infection with methicillin-resistant Staphylococcus aureus (MRSA). Topical application of AKACID Plus at concentrations of > or =0.5% was as effective as mupirocin 2% cream in the treatment of superficial skin infection with MRSA.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 51 9  شماره 

صفحات  -

تاریخ انتشار 2007